Document Detail

Curve of amniotic fluid index measurements in low-risk pregnancy.
MedLine Citation:
PMID:  17230287     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To establish a curve of amniotic fluid index [AFI] measurements from the 20th to the 42nd week of pregnancy. METHODS: A prospective and descriptive study was performed, in which an independent sample of 2,868 low-risk pregnant women were studied using routine ultrasound, including fetal biometry and measurement of AFI. Data were analysed using multiple linear regression, and constructing a curve using 2.5th, 10th, 50th, 90th and 97.5th percentiles of the AFI measurements, according to gestational age, and after submitting values to smoothing process using quadratic polynomial adjustment. RESULTS: There was a significant variation in AFI measurements at the different gestational ages. The 50th percentile remained practically constant at approximately 150 mm between the 20th and 33rd week, after which there was a decline in volume, which became evident after the 38th week. At the 40th week, the 10th percentile was around 62 mm and the 2.5th percentile around 33 mm. CONCLUSIONS: The curve of percentiles of AFI measurements in low-risk pregnant women showed significant decrease with gestational age, especially after the 33rd week. These data should be validated for a diagnosis of increased or decreased volumes of amniotic fluid at specific gestational ages.
Maria Regina Machado; Jose Guilherme Cecatti; Fabiana Krupa; Anibal Faundes
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  86     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  2007  
Date Detail:
Created Date:  2007-01-18     Completed Date:  2007-02-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  37-41     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, Brazil.
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MeSH Terms
Amniotic Fluid / physiology*,  ultrasonography
Gestational Age
Linear Models
Middle Aged
Pregnancy / physiology*
Pregnancy Trimester, Second / physiology
Pregnancy Trimester, Third / physiology
Prospective Studies
Reference Values
Ultrasonography, Prenatal*

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