| Current use of aspirin and antithrombotic agents in the United States among outpatients with atherothrombotic disease (from the REduction of Atherothrombosis for Continued Health [REACH] Registry). | |
| | |
MedLine Citation:
|
PMID: 20152237 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Despite its proven efficacy, low cost, and wide availability, aspirin remains underused. We examined current aspirin use and determined factors that influence its use among outpatients in the United States (US). The REduction of Atherothrombosis for Continued Health (REACH) Registry is an international, prospective, longitudinal study of >68,000 outpatients with established atherothrombosis or >or=3 atherothrombotic risk factors. The rates of aspirin use were compared in various patient subgroups. Multivariate logistic regression models were constructed to determine the factors influencing the baseline use of aspirin and other antithrombotic agents in the US population. Approximately 70% of 25,686 US outpatients were treated with aspirin, with greater use in the Midwest and among men, whites, and those aged <65 years. Among aspirin users, 18% took other antiplatelet agents and 6% took oral anticoagulants. Low-dose aspirin (<or=100 mg/day) was used in approximately 2/3 of aspirin users. Of patients not taking aspirin, 1/2 were receiving oral anticoagulants or other antiplatelet agents. However, 15% of patients used no antithrombotic agent at all. Female gender, current smoking, or having diabetes mellitus were predictors of a lack of antithrombotic use; white race, atrial fibrillation or vascular disease, the use of other risk-reducing medications, or treatment by a cardiologist were associated with a greater likelihood of receiving antithrombotic therapy. In conclusion, approximately 1/4 of US patients with vascular disease are not treated with aspirin for secondary prevention, and 15% are not treated with any antithrombotic agent. |
| | |
Authors:
|
Christopher P Cannon; Karen E Rhee; Robert M Califf; William E Boden; Alan T Hirsch; Mark J Alberts; Greg Cable; Mingyuan Shao; E Magnus Ohman; P Gabriel Steg; Kim A Eagle; Deepak L Bhatt; |
Related Documents
:
|
18178417 - Early and long-term clinical results of angiojet rheolytic thrombectomy in patients wit... 19127387 - Risk-group targeted inferior vena cava filter placement in gastric bypass patients. 7853597 - Comparative efficacy and complications of vena caval filters. 19738137 - Improved oral anticoagulation after a dietary vitamin k-guided strategy: a randomized c... 1871677 - Early and long-term results of pneumatic dilation in the treatment of oesophageal achal... 20233137 - Graft patency after off-pump versus on-pump coronary artery surgery in high-risk patients. |
Publication Detail:
|
Type: Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't Date: 2010-01-05 |
Journal Detail:
|
Title: The American journal of cardiology Volume: 105 ISSN: 1879-1913 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2010 Feb |
Date Detail:
|
Created Date: 2010-02-15 Completed Date: 2010-03-19 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
|
Languages: eng Pagination: 445-52 Citation Subset: AIM; IM |
Copyright Information:
|
Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
|
TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. cpcannon@partners.org |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Aspirin / therapeutic use* Coronary Artery Disease / drug therapy* Coronary Thrombosis / drug therapy* Drug Therapy, Combination Female Fibrinolytic Agents / therapeutic use* Humans Logistic Models Male Middle Aged Multivariate Analysis Platelet Aggregation Inhibitors / therapeutic use* Prospective Studies Registries Risk Factors Treatment Outcome United States World Health |
| Chemical | |
Reg. No./Substance:
|
0/Fibrinolytic Agents; 0/Platelet Aggregation Inhibitors; 50-78-2/Aspirin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Relation between thrombolysis in myocardial infarction risk score and one-year outcomes for patients...
Next Document: Noninvasive assessment of gender differences in coronary plaque composition with multidetector compu...