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Current update on the randomized controlled trials of intracranial aneurysms.
MedLine Citation:
PMID:  22125740     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Endovascular coiling has become the primary treatment modality for the treatment of intracranial ruptured aneurysms in many centers. A multicenter randomized controlled trial (RCT), ISAT study, has demonstrated that endovascular coiling of ruptured intracranial aneurysms has benefits over surgical clipping in those patients suitable for either treatment. Because RCT comparing conservative management with surgical clipping and with endovascular coiling have not been performed to date for unruptured intracranial aneurysms, the best management for unruptured aneurysm remains unclear. A RCT is ongoing to answer the question whether active treatment can improve the outcome of patients with unruptured intracranial aneurysms as compared with observation.
Woong Yoon
Publication Detail:
Type:  Journal Article     Date:  2011-02-28
Journal Detail:
Title:  Neurointervention     Volume:  6     ISSN:  2233-6273     ISO Abbreviation:  Neurointervention     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-11-29     Completed Date:  2012-10-02     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101561462     Medline TA:  Neurointervention     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  1-5     Citation Subset:  -    
Department of Radiology, Chonnam National University Medical School, Gwangju, Korea.
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