Document Detail


Current trends in the treatment of psoriasis.
MedLine Citation:
PMID:  6859798     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
New treatment modalities are now available in the management of psoriasis. We report our local studies on these new modalities. Application of dithranol for 1/2 hour is just as effective as when applied for 24 hours. This means less staining of the skin, clothes and no more burns. Oral retinoids gave more than 70% improvement in six of the seven patients with recalcitrant psoriasis. Oral retinoids produced more than 75% improvement in all eight patients with pustular psoriasis. PUVA therapy gave a complete clearance rate of 77% with an average of 25 sessions of treatment and an average total UVA dose of 346 J/cm2. However REPUVA (retinoids and PUVA) produced a complete clearance rate of 73% with an average of 18 sessions of treatment and an average total UVA dose of 142 J/cm2. The newer forms of treatment together with the established therapies have tremendously improved the total management of patients with psoriasis.
Authors:
T Thirumoorthy; V S Rajan
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Annals of the Academy of Medicine, Singapore     Volume:  12     ISSN:  0304-4602     ISO Abbreviation:  Ann. Acad. Med. Singap.     Publication Date:  1983 Jan 
Date Detail:
Created Date:  1983-07-08     Completed Date:  1983-07-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7503289     Medline TA:  Ann Acad Med Singapore     Country:  SINGAPORE    
Other Details:
Languages:  eng     Pagination:  39-44     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Anthralin / therapeutic use
Drug Therapy, Combination
Etretinate / administration & dosage,  therapeutic use*
Female
Humans
Male
Methotrexate / administration & dosage,  therapeutic use
Middle Aged
PUVA Therapy
Psoriasis / drug therapy*
Time Factors
Tretinoin / analogs & derivatives*
Chemical
Reg. No./Substance:
302-79-4/Tretinoin; 480-22-8/Anthralin; 54350-48-0/Etretinate; 59-05-2/Methotrexate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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