Document Detail

Current treatment strategies in elderly patients with metastatic colorectal cancer.
MedLine Citation:
PMID:  17553199     Owner:  NLM     Status:  MEDLINE    
Colorectal cancer (CRC) is one of the most common cancers in the Western world, with > 500,000 new cases diagnosed each year. One of the strongest risk factors for colon cancer is age. The incidence rates rise from 10 in 100,000 at age 40-45 years to 300 in 100,000 at age 75-80 years, with the median age at diagnosis of CRC being 71 years. With the general demographic shift toward an aging population, the number of people aged > 65 years is expected to increase. This article reviews the development of treatment for elderly patients with metastatic CRC, from single-agent fluoropyrimidines to combination therapies.
Hendrik-Tobias Arkenau; Yu Jo Chua; David Cunningham
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical colorectal cancer     Volume:  6     ISSN:  1533-0028     ISO Abbreviation:  Clin Colorectal Cancer     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-06-07     Completed Date:  2007-07-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101120693     Medline TA:  Clin Colorectal Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  508-15     Citation Subset:  IM    
Department of Medical Oncology, Royal Marsden Hospital-London and Sutton, Surrey, United Kingdom.
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MeSH Terms
Antineoplastic Agents / therapeutic use*
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Colorectal Neoplasms / drug therapy*,  secondary
Reg. No./Substance:
0/Antineoplastic Agents

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