Document Detail


Current treatment strategies in elderly patients with metastatic colorectal cancer.
MedLine Citation:
PMID:  17553199     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Colorectal cancer (CRC) is one of the most common cancers in the Western world, with > 500,000 new cases diagnosed each year. One of the strongest risk factors for colon cancer is age. The incidence rates rise from 10 in 100,000 at age 40-45 years to 300 in 100,000 at age 75-80 years, with the median age at diagnosis of CRC being 71 years. With the general demographic shift toward an aging population, the number of people aged > 65 years is expected to increase. This article reviews the development of treatment for elderly patients with metastatic CRC, from single-agent fluoropyrimidines to combination therapies.
Authors:
Hendrik-Tobias Arkenau; Yu Jo Chua; David Cunningham
Related Documents :
2524339 - Childhood diabetes mellitus: an increasing incidence.
1342799 - Epidemiology of dengue/dengue hemorrhagic fever in malaysia--a retrospective epidemiolo...
20952989 - Dermatophytoses in a desert district of western rajasthan.
1212409 - Cancer and ageing in mice and men.
18271799 - Trends during a half century in relative squamous cell carcinoma distribution by body s...
8598179 - Incidence and clinical characterization of unprovoked seizures in adults: a prospective...
9777379 - Factors influencing intensive care unit survival for critically ill elderly patients.
10905529 - Weight gain continues in the 1990s: 10-year trends in weight and overweight from the ca...
20085549 - Serum levels of igf1 are a useful predictor of retinopathy of prematurity.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical colorectal cancer     Volume:  6     ISSN:  1533-0028     ISO Abbreviation:  Clin Colorectal Cancer     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-06-07     Completed Date:  2007-07-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101120693     Medline TA:  Clin Colorectal Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  508-15     Citation Subset:  IM    
Affiliation:
Department of Medical Oncology, Royal Marsden Hospital-London and Sutton, Surrey, United Kingdom.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Animals
Antineoplastic Agents / therapeutic use*
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Colorectal Neoplasms / drug therapy*,  secondary
Humans
Chemical
Reg. No./Substance:
0/Antineoplastic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Supporting healthy eating among preschoolers: challenges for child care staff.
Next Document:  Phase II trial of oxaliplatin/irinotecan/5-fluorouracil/leucovorin for metastatic colorectal cancer.