Document Detail


Current treatment for multiple sclerosis
MedLine Citation:
PMID:  20106633     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Several drugs are now available to treat multiple sclerosis. MS treatment has included immunomodulatory agents for 15 years; monoclonal antibody therapies have recently been added. IFN beta and Glatiramer acetate are effective in reducing relapses and lesions visible on magnetic resonance imaging (MRI) in patients with MS. Natalizumab, a monoclonal antibody, reduces the short-term risk of increasing disability and the rate of clinical relapse in patients with relapsing MS. Clinical trials are currently underway to assess the efficacy of other monoclonal antibodies and immunosuppressors. In the future, remyelinating and neuroprotective approach offers new perpectives.
Authors:
Caroline Papeix; Catherine Lubetzki; Olivier Lyon-Caen
Publication Detail:
Type:  English Abstract; Journal Article     Date:  2010-01-27
Journal Detail:
Title:  Presse m?dicale (Paris, France : 1983)     Volume:  39     ISSN:  0755-4982     ISO Abbreviation:  Presse Med     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-08     Completed Date:  2010-04-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8302490     Medline TA:  Presse Med     Country:  France    
Other Details:
Languages:  fre     Pagination:  381-8     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2009 Elsevier Masson SAS. All rights reserved.
Affiliation:
F?d?ration des maladies du syst?me nerveux, groupe hospitalier Piti?-Salp?tri?re, 75651 Paris cedex 13, France. caroline.papeix@psl.aphp.fr
Vernacular Title:
Traitements actuels de la scl?rose en plaques.
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MeSH Terms
Descriptor/Qualifier:
Humans
Immunologic Factors / therapeutic use
Multiple Sclerosis / drug therapy*
Chemical
Reg. No./Substance:
0/Immunologic Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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