| Current treatment of hepatitis B infection: where do the new nucleos(t)ide analogues fit in? | |
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MedLine Citation:
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PMID: 21550145 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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One of the most important advances made in the treatment of chronic hepatitis B infection has been the development of nucleos(t)ide analogues. The first antiviral agents used had limited efficacy due to the high resistance rate. However, in the last few years, new agents (tenofovir, entecavir) have been developed with greater antiviral potency and a lower resistance rate. Consequently, these agents are considered to be the treatment of choice in the most recent clinical guidelines. Nevertheless, interferon may still play an important role in the treatment of hepatitis B in selected patients. Moreover, in some contexts, such as renal insufficiency, pregnancy or immunosuppression, the role of the new oral antiviral agents has not been precisely defined. The present review analyzes these aspects, as well as some of the particular features of the management of patients treated with nucleos(t)ide analogues. |
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Authors:
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Javier Fuentes Olmo; Rafael Uribarrena Amézaga |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-5 |
Journal Detail:
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Title: Gastroenterologia y hepatologia Volume: - ISSN: 0210-5705 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-5-9 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8406671 Medline TA: Gastroenterol Hepatol Country: - |
Other Details:
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Languages: SPA Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier España, S.L. All rights reserved. |
Affiliation:
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Servicio de Aparato Digestivo, Hospital Universitario Miguel Servet, Zaragoza, España. |
Vernacular Title:
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Tratamiento actual de la hepatitis B: ¿dónde encajan los nuevos análogos de los núcleos(t)idos? |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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