Document Detail


Current themes in molecular pediatrics: molecular medicine and its applications.
MedLine Citation:
PMID:  20170480     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We focus on themes that are derived from clinical practice and research in the field of genetic diseases of bone and inborn errors of metabolism but may be of more general interest as they indicate some trends in molecular medicine as related to pediatrics. Identifying the disease-causing mechanism brings about efficient therapeutic strategies and discovering the mutant genotype in the near future may become helpful for devising custom-built molecular responses. At the same time, the transition of therapy from the experimental phase to industrial application is difficult as there may be novel roles (and potentially conflicting interests) between physicians, patient organisations, governmental agencies and the pharmaceutical industry. Awareness of these potential conflicts may help in recognizing and dealing with these issues.
Authors:
Andrea Superti-Furga; Livia Garavelli
Publication Detail:
Type:  Journal Article; Review     Date:  2010-02-19
Journal Detail:
Title:  Italian journal of pediatrics     Volume:  36     ISSN:  1824-7288     ISO Abbreviation:  Ital J Pediatr     Publication Date:  2010  
Date Detail:
Created Date:  2010-03-24     Completed Date:  2010-10-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101510759     Medline TA:  Ital J Pediatr     Country:  England    
Other Details:
Languages:  eng     Pagination:  20     Citation Subset:  IM    
Affiliation:
Centre for Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany. asuperti@uniklinik-freiburg.de
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MeSH Terms
Descriptor/Qualifier:
Child
Genetic Diseases, Inborn / genetics*
Genetic Techniques / trends*
Humans
Molecular Biology / trends*
Pediatrics / methods*
Comments/Corrections

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