| Current strategies for ischemic stroke prevention: role of multimodal combination therapies. | |
| | |
MedLine Citation:
|
PMID: 17934879 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Stroke remains a global leading cause of death and long-term disability, highlighting the need for more effective treatment approaches. The majority of strokes are of ischemic origin, often caused by large- or small-artery atherothrombosis, or cardioembolism. Considering the systemic nature of the atherothrombotic disease process, stroke patients are at increased risk for ischemic events in several vascular territories: cerebral, coronary and peripheral. Due to the limited options for acute stroke therapies, stroke prevention is an important therapeutic approach. In addition to the management of modifiable risk factors such as hypertension, dyslipidemia and smoking through pharmacotherapy or lifestyle adjustments, anticoagulants, surgical and perhaps endovascular approaches are indicated in certain patients. Antiplatelet therapies using various agents are a cornerstone of secondary stroke prevention. To ensure the appropriate continuum of care after hospitalization for ischemic stroke, some interventions for the prevention of recurrent ischemic stroke should be initiated during the acute hospitalization setting and maintained in the out-patient setting. |
| | |
Authors:
|
M J Alberts; B Ovbiagele |
Related Documents
:
|
7115069 - Prophylactic carotid endarterectomy for asymptomatic bruit. a look at cardiac risk. 9825009 - Applying the results of trials and systematic reviews to individual patients. 19137129 - Pathophysiology and therapeutic strategies in the management of stroke: an update. 2432519 - Importance of atrial electrophysiology in the work-up of cerebral ischemic attacks. 9236329 - Is an integrated approach warranted for concomitant carotid and coronary artery disease? 12499489 - Strokes restricted to the insular cortex. 3620249 - Global and regional right ventricular function after acute myocardial infarction: depen... 18832899 - Correlation of vascular endothelial growth factor with the severity of thalassemia inte... 16928169 - Use of the profunda femoris to facilitate closure of an antegrade puncture with the sta... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2007-10-15 |
Journal Detail:
|
Title: Journal of neurology Volume: 254 ISSN: 0340-5354 ISO Abbreviation: J. Neurol. Publication Date: 2007 Oct |
Date Detail:
|
Created Date: 2007-10-25 Completed Date: 2008-02-29 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0423161 Medline TA: J Neurol Country: Germany |
Other Details:
|
Languages: eng Pagination: 1414-26 Citation Subset: IM |
Affiliation:
|
Dept. of Neurology, Northwestern University, Feinberg School of Medicine, 710 North Lake Shore Drive, Room 1420, Chicago, IL 60611, USA. m-alberts@northwestern.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Antihypertensive Agents Combined Modality Therapy* Fibrinolytic Agents Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors Ischemia / complications Risk Factors Stroke / etiology, prevention & control* Tissue Plasminogen Activator |
| Chemical | |
Reg. No./Substance:
|
0/Antihypertensive Agents; 0/Fibrinolytic Agents; 0/Hydroxymethylglutaryl-CoA Reductase Inhibitors; EC 3.4.21.68/Tissue Plasminogen Activator |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Task-induced activation and hemispheric dominance in cerebral circulation during gum chewing.
Next Document: Substantia nigra hyperechogenicity correlates with clinical status and number of Parkin mutated alle...