Document Detail

Current status on stentless aortic bioprosthesis: a clinical and experimental perspective.
MedLine Citation:
PMID:  22219434     Owner:  NLM     Status:  MEDLINE    
Introduction of stentless valves into clinical practice has not replaced stented valve prosthesis as expected a decade ago. With respect to clinical parameters such as transvalvular pressure differences, left ventricular mass regression as well as a possible survival benefit, there are many contradictory studies published. The overall dilemma is the absence of large randomized studies. This review, therefore, focuses on two issues: Experimental research in order to disclose design advantages or drawbacks and clinical trials expressing the real benefit or risk for the patient. In general, both clinical and experimental studies show that stentless valves have several biomechanical and haemodynamic benefits when compared with stented valves though new generation pericardial valves have excellent blood flow profiles. However, stentless and stented valves seem to perform equally well when it comes to various clinical parameters. In most cases, a stented valve is therefore preferable because of the simpler implantation technique. In order to gain a more widespread clinical use, the design of the stentless valve needs to be improved in order to simplify the implantation.
Jonas Amstrup Funder
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Publication Detail:
Type:  Journal Article; Review     Date:  2011-12-21
Journal Detail:
Title:  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery     Volume:  41     ISSN:  1873-734X     ISO Abbreviation:  Eur J Cardiothorac Surg     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-03-16     Completed Date:  2012-06-19     Revised Date:  2013-02-22    
Medline Journal Info:
Nlm Unique ID:  8804069     Medline TA:  Eur J Cardiothorac Surg     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  790-9     Citation Subset:  IM    
Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Skejby, Denmark.
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MeSH Terms
Aortic Valve / physiology,  surgery*
Aortic Valve Stenosis / surgery
Heart Valve Prosthesis*
Heart Valve Prosthesis Implantation / methods
Prosthesis Design
Randomized Controlled Trials as Topic
Comment In:
Eur J Cardiothorac Surg. 2013 Feb;43(2):454   [PMID:  23319491 ]
Eur J Cardiothorac Surg. 2013 Feb;43(2):453-4   [PMID:  22822107 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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