Document Detail

Current status of estimated glomerular filtration rate (eGFR) equations for Asians and an approach to create a common eGFR equation.
MedLine Citation:
PMID:  20586948     Owner:  NLM     Status:  MEDLINE    
CKD is now recognized as life-threatening disease and various countermeasures are implemented worldwide. The most important step to overcome CKD is early detection and evaluation. Equation for estimating GFR is the necessary tool for this step. This is also useful to follow-up CKD patients in routine clinical settings. Currently, most commonly used equation is original and re-expressed MDRD formula. For Asians, ethnic co-efficient is needed when applying these formulas. Ethnic co-efficient is different among Asian countries. Recently, different original equations have been developed in several Asian countries. At the present time, it is not clear to develop a single common eGFR equation fit for Asians. There are several factors that affect GFR estimation. These include ethnicity, reference method to measure GFR, method of creatinine measurement and calibration. Towards the future, Asian collaborative study is necessary to validate and standardize eGFR equations.
Seiichi Matsuo; Yoshinari Yasuda; Enyu Imai; Masaru Horio
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Nephrology (Carlton, Vic.)     Volume:  15 Suppl 2     ISSN:  1440-1797     ISO Abbreviation:  Nephrology (Carlton)     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-30     Completed Date:  2010-10-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9615568     Medline TA:  Nephrology (Carlton)     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  45-8     Citation Subset:  IM    
Department of Nephrology, Nagoya University Hospital, Nagoya University Graduate School of Medicine, Nagoya, Japan.
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MeSH Terms
Asian Continental Ancestry Group*
Glomerular Filtration Rate*
Kidney Failure, Chronic / diagnosis*,  ethnology,  physiopathology

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