Document Detail

Current status of endomyocardial biopsy.
MedLine Citation:
PMID:  22033254     Owner:  NLM     Status:  MEDLINE    
Endomyocardial biopsy (EMB) is widely used for surveillance of cardiac allograft rejection and for the diagnosis of unexplained ventricular dysfunction. Typically, EMB is performed through the jugular or femoral veins and is associated with a serious acute complication rate of less than 1% using current flexible bioptomes. Although it is accepted that EMB should be used to monitor for rejection after transplant, use of EMB for the diagnosis of various myocardial diseases is controversial. Diagnosis of myocardial disease in the nontransplant recipient is often successful via noninvasive investigations including laboratory evaluation; echocardiography, nuclear studies, and magnetic resonance imaging can yield specific diagnoses in the absence of invasive EMB. Therefore, use of the technique is patient specific and depends on the potential prognostic and treatment information gained by establishing a pathologic diagnosis beyond noninvasive testing.
Aaron M From; Joseph J Maleszewski; Charanjit S Rihal
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Mayo Clinic proceedings     Volume:  86     ISSN:  1942-5546     ISO Abbreviation:  Mayo Clin. Proc.     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-10-28     Completed Date:  2011-12-20     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  0405543     Medline TA:  Mayo Clin Proc     Country:  England    
Other Details:
Languages:  eng     Pagination:  1095-102     Citation Subset:  AIM; IM    
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MeSH Terms
Bayes Theorem
Biopsy, Needle* / methods
Cardiomyopathies / diagnosis
Echocardiography, Transesophageal
Endocardium / pathology*
Graft Rejection / diagnosis*
Heart Neoplasms / diagnosis
Heart Transplantation*
Magnetic Resonance Imaging
Myocarditis / pathology
Myocardium / pathology*
Practice Guidelines as Topic
Sarcoidosis / diagnosis
Transplantation, Homologous

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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