| Current remedies for vitiligo. | |
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MedLine Citation:
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PMID: 20149899 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Vitiligo is a disorder with complex causes and is a type of autoimmune disease in which the immune system targets the body's own pigment cells and tissues. Our aim is to present an overall view of the current remedies widely adopted for the treatment of vitiligo. Medical treatments target the immune system, and try to reverse the destruction. The goal is to restore the skin's color by restoring healthy melanocytes to the affected area. Apart from melanocytes, vitiligo autoantigens appear also on other cells. Even though antibodies to pigment cells are not an agent of vitiligo, the most valuable contribution is that anti-melanocyte antibody reactivity can help in identifying relevant antigens. T cells from vitiligo skin are highly reactive towards melanoma cells and serve as an effective source to treat melanoma and stays as a solution for vitiligo. There have been many treatments to cure vitiligo such as use of steroid creams, PUVA (psoralen and ultraviolet A light), narrow band UVB (ultraviolet B), various surgical techniques, vitamin D analogues and pseudocatalase. These treatments are subjected for undesired side effects whereas some herbal and natural treatments act against the immune system with no side effects. |
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Authors:
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M Abu Tahir; K Pramod; S H Ansari; Javed Ali |
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Publication Detail:
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Type: Journal Article; Review Date: 2010-02-08 |
Journal Detail:
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Title: Autoimmunity reviews Volume: 9 ISSN: 1873-0183 ISO Abbreviation: Autoimmun Rev Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-11 Completed Date: 2010-09-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101128967 Medline TA: Autoimmun Rev Country: Netherlands |
Other Details:
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Languages: eng Pagination: 516-20 Citation Subset: IM |
Copyright Information:
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2010 Elsevier B.V. All rights reserved. |
Affiliation:
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Department of Pharmaceutics, Jamia Hamdard, Hamdard Nagar, New Delhi, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Autoantibodies / immunology* Autoimmunity Cell Transplantation Humans Melanocytes / drug effects, immunology* PUVA Therapy Phytotherapy* Steroids / therapeutic use Vitiligo / immunology*, therapy* |
| Chemical | |
Reg. No./Substance:
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0/Autoantibodies; 0/Steroids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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