| Current and potential uses for DNA microarrays in transplantation medicine: lessons from other disciplines. | |
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MedLine Citation:
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PMID: 12889990 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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DNA microarrays are used to study simultaneous gene expression in thousands of genes. This tool has moved beyond proof-of-principle and its integration into medical practice is slowly becoming a reality. This technology has enabled unparalleled progress into the study of complex polygenic diseases. Although cancer research introduced DNA microarrays into the medical arena other disciplines are beginning to exploit the power of this technology to advance medical research. In this review we outline aspects of the design of a microarray experiment from the choice of platform, through the experimental procedure to the analysis of the results. We review the current applications and speculate on potential applications of this technology with particular reference to transplantation medicine. |
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Authors:
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A Boussioutas; I Haviv |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Tissue antigens Volume: 62 ISSN: 0001-2815 ISO Abbreviation: Tissue Antigens Publication Date: 2003 Aug |
Date Detail:
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Created Date: 2003-07-31 Completed Date: 2004-04-16 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 0331072 Medline TA: Tissue Antigens Country: Denmark |
Other Details:
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Languages: eng Pagination: 93-103 Citation Subset: IM |
Affiliation:
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Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Victoria, Australia. a.boussioutas@pmci.unimelb.edu.au |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Computational Biology Humans Neoplasms / etiology, genetics Oligonucleotide Array Sequence Analysis* Organ Transplantation* Pedigree |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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