Document Detail


Current perspectives on the management and prevention of antiretroviral-associated lipoatrophy.
MedLine Citation:
PMID:  18703527     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lipoatrophy (LA) is a common and now well-recognized complication of highly active antiretroviral therapy (HAART). Over the last decade as knowledge of the mechanisms behind LA has developed, several antiretroviral drugs, in particular, have emerged as the likely agents responsible for this complication. This has been supported by studies comparing alternative HAART regimens and by those in which HAART regimens have been modified with a resulting impact on LA. In this article, we review the evidence underlying the current perspectives on the development of LA and the strategies employed to manage or avoid it.
Authors:
David Richard Phillips; Phillip Hay
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-08-13
Journal Detail:
Title:  The Journal of antimicrobial chemotherapy     Volume:  62     ISSN:  1460-2091     ISO Abbreviation:  J. Antimicrob. Chemother.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-10-13     Completed Date:  2008-12-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7513617     Medline TA:  J Antimicrob Chemother     Country:  England    
Other Details:
Languages:  eng     Pagination:  866-71     Citation Subset:  IM    
Affiliation:
Courtyard Clinic, St George's Hospital NHS Trust, Blackshaw Road, Tooting, London SW17 0QT, UK.
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MeSH Terms
Descriptor/Qualifier:
Antiretroviral Therapy, Highly Active / adverse effects*,  methods*
HIV Infections / complications*,  drug therapy*
HIV-Associated Lipodystrophy Syndrome / chemically induced,  prevention & control*,  therapy*
Humans

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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