Document Detail

Current methodology for oxygen-15 production for clinical use.
MedLine Citation:
PMID:  2822617     Owner:  NLM     Status:  MEDLINE    
The radionuclide oxygen-15, half-life 2.05 min, is used in simple chemical forms to study oxygen metabolism, blood flow and blood volume in man, using the technique of positron emission tomography (PET). The production of 15O and the preparation of [15O]O2, [15O]CO2, [15O]CO and [15O]H2O is now well established in several PET centres in Europe, North America and Japan. In order to provide a practical design and operational data base for others intending to make use of these techniques an EEC task group representing four European laboratories routinely using 15O in PET studies was set up to review the current practice of 15O production purification and quality control of the clinically useful products.
J C Clark; C Crouzel; G J Meyer; K Strijckmans
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes     Volume:  38     ISSN:  0883-2889     ISO Abbreviation:  Int J Rad Appl Instrum A     Publication Date:  1987  
Date Detail:
Created Date:  1987-11-30     Completed Date:  1987-11-30     Revised Date:  2009-06-04    
Medline Journal Info:
Nlm Unique ID:  8611097     Medline TA:  Int J Rad Appl Instrum A     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  597-600     Citation Subset:  IM    
MRC Cyclotron Unit, Hammersmith Hospital, London, U.K.
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MeSH Terms
Carbon Dioxide
Chromatography, Gas
Oxygen Radioisotopes / diagnostic use*
Reg. No./Substance:
0/Oxygen Radioisotopes; 124-38-9/Carbon Dioxide; 7732-18-5/Water; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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