| Current medical treatments of dyspepsia and irritable bowel syndrome. | |
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MedLine Citation:
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PMID: 20951913 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Dyspepsia is a highly prevalent condition characterized by symptoms originating in the gastroduodenal region without underlying organic disorder. Treatment modalities include acid-suppressive drugs, gastroprokinetic drugs, Helicobacter pylori eradication therapy, tricyclic antidepressants, and psychological therapies. Irritable bowel syndrome is a multifactorial, lower functional gastrointestinal disorder involving disturbances of the brain-gut axis. The pathophysiology provides the basis for pharmacotherapy: abnormal gastrointestinal motor functions, visceral hypersensitivity, psychosocial factors, intraluminal changes, and mucosal immune activation. Medications targeting chronic constipation or diarrhea may also relieve irritable bowel syndrome. Novel approaches to treatment require approval, and promising agents are guanylate cyclase cagonists, atypical benzodiazepines, antibiotics, immune modulators, and probiotics. |
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Authors:
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Michael Camilleri; Jan F Tack |
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10442423 - Irritable bowel syndrome in patients with blastocystis hominis infection. 10472893 - D-lactic acidosis in short bowel syndrome. 3798083 - Cerebellar ataxia in infectious mononucleosis. |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Gastroenterology clinics of North America Volume: 39 ISSN: 1558-1942 ISO Abbreviation: Gastroenterol. Clin. North Am. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-10-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8706257 Medline TA: Gastroenterol Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 481-93 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Clinical Enteric Neuroscience Translational and Epidemiological Research, Mayo Clinic College of Medicine, Charlton 8-110, 200 First Street Southwest, Rochester, MN 55905, USA. camilleri.michael@mayo.edu |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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