| Current issues in the clinical management of invasive candida infections - the AGIHO, DMykG, ÖGMM and PEG web-based survey and expert consensus conference 2009. | |
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MedLine Citation:
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PMID: 21554423 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The objectives of this study were to identify unsolved issues in the management of invasive candidiasis, identify controversies and achieve consensus. The German Speaking Mycological Society (Deutschsprachige Mykologische Gesellschaft, DMykG e.V.) asked other German infectious diseases (ID) and mycological societies to submit unsolved issues concerning the diagnosis and treatment of fungal infections. Based on these contributions, a digital web-based questionnaire of 12 questions on Candida infections was designed to be completed by experts of the participating societies. Controversial results were identified by a mathematical model and were discussed at a consensus conference during the 43rd Annual Meeting of the DMykG e.V. in Cologne, Germany. Forty-two individuals completed the questionnaire. Analysis showed a strong consensus on treatment indications, choice of antifungals for clinical situations, handling of central venous catheters, duration of treatment and role of susceptibility testing. Opinions diverged on: initial treatment of haemodynamically stable neutropenic and haemodynamically unstable non-neutropenic patients, step down to oral treatment and the differential role of the echinocandins. These questions were presented for discussion at the expert consensus conference. In three of four questions, consensus was achieved. A two-step approach - web-based survey plus classical panel discussion - allows to capture expeditiously the opinions of a large and diverse group of individuals, to identify controversial issues and to resolve them in a personal, interactive setting. Thus, expert consensus was achieved on nine of 12 important questions on how to treat invasive candidiasis. |
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Authors:
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M Karthaus; M J G T Rüping; O A Cornely; A Steinbach; A H Groll; C Lass-Flörl; H Ostermann; M Ruhnke; J J Vehreschild |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-10 |
Journal Detail:
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Title: Mycoses Volume: - ISSN: 1439-0507 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-5-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8805008 Medline TA: Mycoses Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 Blackwell Verlag GmbH. |
Affiliation:
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Cancer Center Munich South, Klinikum Neuperlach and Harlaching, Munich, Germany 1st Department of Internal Medicine, University of Cologne, Cologne, Germany Clinical Trials Centre Cologne, ZKS Köln, University of Cologne, Cologne, Germany Center for Integrated Oncology CIO KölnBonn, University of Cologne, Cologne, Germany Infectious Diseases Research Program, Centre for Bone Marrow Transplantation and Department of Paediatric Haematology/Oncology, Children's University Hospital, Münster, Germany Department of Hygiene, Microbiology and Social Medicine, Innsbruck Medical University, Innsbruck, Austria Medizinische Klinik III, Klinikum der Universität München-Großhadern, München, Germany Medizinische Klinik und Poliklinik II, Charité Universitätsmedizin, Campus Charité Mitte, Berlin, Germany. |
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