Document Detail


Current and future pharmacologic treatment of sarcopenia.
MedLine Citation:
PMID:  21824556     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sarcopenia is a complex multifactorial condition that can by treated with multimodal approaches. No pharmacologic agent to prevent or treat sarcopenia has been as efficacious as exercise (mainly resistance training) in combination with nutritional intervention (adequate protein and energy intake). However, performing resistance training sessions and following nutritional advice can be challenging, especially for frail, sarcopenic, elderly patients, and results remain only partial. Therefore, new pharmacologic agents may substantially reduce the functional decline in older people. This article reviews the new pharmacologic agents currently being assessed for treating sarcopenia.
Authors:
Yves Rolland; Graziano Onder; John E Morley; Sophie Gillette-Guyonet; Gabor Abellan van Kan; Bruno Vellas
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Publication Detail:
Type:  Journal Article; Review     Date:  2011-05-14
Journal Detail:
Title:  Clinics in geriatric medicine     Volume:  27     ISSN:  1879-8853     ISO Abbreviation:  Clin. Geriatr. Med.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-09     Completed Date:  2011-10-05     Revised Date:  2013-05-02    
Medline Journal Info:
Nlm Unique ID:  8603766     Medline TA:  Clin Geriatr Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  423-47     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Inserm U1027, University of Toulouse III, Avenue Jules Guesdes, France. rolland.y@chu-toulouse.fr
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MeSH Terms
Descriptor/Qualifier:
Aged
Aging
Angiotensin-Converting Enzyme Inhibitors / therapeutic use*
Drug Therapy / trends*
Frail Elderly
Hormones / therapeutic use*
Humans
Muscle Weakness / drug therapy*,  etiology,  physiopathology
Sarcopenia / diagnosis,  drug therapy*,  physiopathology
Chemical
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors; 0/Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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