| Current and future aggressive peripheral T-cell lymphoma treatment paradigms, biological features and therapeutic molecular targets. | |
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MedLine Citation:
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PMID: 19056295 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Prognosis of PTCL is generally poor when treated with conventional chemotherapy regimens used in B-cell aggressive lymphomas. Recent advances in genomic and molecular profiling of PTCL have allowed to further insight this heterogeneous group of neoplasias and their main prognostic factors. This review will try to summarize the main clinical problems related to standard frontline and salvage therapy, including the use of conventional chemotherapy and high-dose, dose-dense and immunotherapeutic strategies, as well as new approaches based on biological knowledge and the use of new drugs or immunotherapy. |
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Authors:
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J Rodríguez; A Gutiérrez; B Martínez-Delgado; G Perez-Manga |
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Publication Detail:
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Type: Journal Article; Review Date: 2008-12-03 |
Journal Detail:
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Title: Critical reviews in oncology/hematology Volume: 71 ISSN: 1879-0461 ISO Abbreviation: Crit. Rev. Oncol. Hematol. Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-08-03 Completed Date: 2009-10-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8916049 Medline TA: Crit Rev Oncol Hematol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 181-98 Citation Subset: IM |
Affiliation:
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Service of Oncology, General University Hospital Gregorio Marañon, Madrid, Spain. joseguez89@hotmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antineoplastic Combined Chemotherapy Protocols
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therapeutic use* Chromosome Aberrations Drug Delivery Systems / methods, trends* Gene Expression Profiling Gene Expression Regulation, Neoplastic Genomics / methods Humans Immunotherapy / methods, trends Lymphoma, T-Cell, Peripheral / diagnosis, genetics, pathology*, therapy* Neoplasm Invasiveness Stem Cell Transplantation / methods Tumor Markers, Biological / antagonists & inhibitors*, genetics |
| Chemical | |
Reg. No./Substance:
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0/Tumor Markers, Biological |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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