| Current enoxaparin dosing guidelines have dubious credibility. | |
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MedLine Citation:
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PMID: 20581896 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To assess the prescribing practice of enoxaparin in comparison to dosing guidelines. METHOD: A prospective observational chart review of patients who received enoxaparin for the treatment of thrombosis at Dunedin Public Hospital between August 2007 and January 2008. Deviations in dose from guidelines were defined and recorded along with various clinical and demographic data of participants. RESULTS: Fifty-nine patients (62 admissions) were recruited. Dose deviations occurred on 19 (30.7%) occasions. More dose deviations occurred at or close to guideline transition points (total body weight over 90 kg and/or creatinine clearance between 20-40 mL/min). CONCLUSION: Current enoxaparin dosing guidelines are too simplistic and result in discord between dosing in practice and that approved by Medsafe. |
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Authors:
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Hesham Al-Sallami; Sarah Jordan; Ruth Ferguson; Natalie Medlicott; John Schollum; Stephen Duffull |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2010-04-30 |
Journal Detail:
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Title: The New Zealand medical journal Volume: 123 ISSN: 1175-8716 ISO Abbreviation: N. Z. Med. J. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-06-28 Completed Date: 2010-07-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401067 Medline TA: N Z Med J Country: New Zealand |
Other Details:
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Languages: eng Pagination: 62-7 Citation Subset: IM |
Affiliation:
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School of Pharmacy, University of Otago, PO Box 56, Dunedin, New Zealand. hesham.al-sallami@otago.ac.nz |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anticoagulants
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administration & dosage Drug Prescriptions / standards* Enoxaparin / administration & dosage* Humans Practice Guidelines as Topic* Thrombosis / drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 0/Enoxaparin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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