Document Detail


Current controversies in the management of the anemia of prematurity.
MedLine Citation:
PMID:  19167579     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Preterm infants, especially those with extremely low birth weight (ELBW) are exposed to frequent blood draws as part of their care in the neonatal intensive care unit. ELBW infants develop the anemia of prematurity (AOP), a hypo-proliferative anemia marked by inadequate production of erythropoietin (Epo). Treatment of AOP includes red blood cell transfusions, which are given to preterm infants based on indications and guidelines (hematocrit/hemoglobin levels, ventilation and oxygen need, apneas and bradycardias, poor weight gain) that are relatively non-specific. In this article we review recent studies evaluating transfusion guidelines, discuss ways to decrease phlebotomy losses and examine the use of red cell growth factors such as Epo in preventing and treating anemia in preterm infants.
Authors:
Nader Bishara; Robin K Ohls
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in perinatology     Volume:  33     ISSN:  1558-075X     ISO Abbreviation:  Semin. Perinatol.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-01-26     Completed Date:  2009-03-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7801132     Medline TA:  Semin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  29-34     Citation Subset:  IM    
Affiliation:
University of New Mexico School of Medicine, Albuquerque, NM 87131, USA. nbishara@salud.unm.edu
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MeSH Terms
Descriptor/Qualifier:
Anemia, Neonatal / blood,  drug therapy,  therapy*
Blood Transfusion / methods*
Erythropoietin / therapeutic use*
Hematocrit
Humans
Infant, Extremely Low Birth Weight / blood*
Infant, Newborn
Infant, Premature / blood*
Infant, Premature, Diseases / blood,  drug therapy,  therapy*
Chemical
Reg. No./Substance:
11096-26-7/Erythropoietin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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