Document Detail

Current controversies in heart failure with a preserved ejection fraction.
MedLine Citation:
PMID:  20014990     Owner:  NLM     Status:  MEDLINE    
Heart failure with a preserved ejection fraction is a fascinating and multifaceted condition that has provoked enormous debate and a wealth of mechanistic studies. Controversies exist with regard to its nomenclature. If its nomenclature is questioned, one can be certain the pathogenesis is ill understood. If the pathogenesis is disputed, the diagnosis becomes difficult and inconsistent. These diagnostic challenges result in inappropriate recruitment to clinical trials. Therefore, the trials may be underpowered and difficult to interpret. This paper examines contemporary theories of heart failure with a preserved ejection fraction, clarifies the controversies and attempts to resolve the divergences of opinion.
David H MacIver
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Future cardiology     Volume:  6     ISSN:  1744-8298     ISO Abbreviation:  Future Cardiol     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-17     Completed Date:  2010-03-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101239345     Medline TA:  Future Cardiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  97-111     Citation Subset:  IM    
Consultant cardiologist, Department of Cardiology, Taunton & Somerset Hospital, Musgrove Park, Taunton, TA1 5DA, UK.
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MeSH Terms
Heart Failure, Diastolic / classification,  diagnosis*,  etiology,  physiopathology
Heart Failure, Systolic / diagnosis,  physiopathology
Hypertrophy, Left Ventricular / complications,  physiopathology
Stroke Volume*
Terminology as Topic*
Ventricular Function, Left*

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