Document Detail


Current concepts in primary hyperparathyroidism.
MedLine Citation:
PMID:  2613194     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
622 patients were operated on between 1966 and 1988. Urolithiasis was the most common presenting symptom (26%) but routine measurements of serum calcium led to detect 50% cases. At present, the disease is three times more frequent in women than in men. Estrogenic deprivation, neck irradiation (3.4%) and lithium therapy favor the occurrence of hyperparathyroidism (HPT); frequent association with goiter (19.8%), diabetes (8.3%) and multiple endocrine neoplasia (3.5%) has been noticed. Bone Gla protein concentrations correlate with calcium and HPT blood concentrations but do not reflect the severity of bone damage. Dual photon absorptiometry is now available for quantification and follow-up of bone demineralization, especially in asymptomatic forms of HPT.
Authors:
J L Wémeau; E Gilliot-Valtille; J P Bizard; R Leroy; X Marchandise; M Decoulx; C Proye
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hormone research     Volume:  32     ISSN:  0301-0163     ISO Abbreviation:  Horm. Res.     Publication Date:  1989  
Date Detail:
Created Date:  1990-03-13     Completed Date:  1990-03-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0366126     Medline TA:  Horm Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  93-6     Citation Subset:  IM    
Affiliation:
CHU, Lille, France.
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MeSH Terms
Descriptor/Qualifier:
Humans
Hyperparathyroidism / diagnosis,  etiology*,  physiopathology

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