Document Detail


Current concepts in AIDS pathogenesis: insights from the SIV/macaque model.
MedLine Citation:
PMID:  17217334     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The pathogenesis of AIDS has proven to be quite complex and dynamic, with most of the critical events (e.g., transmission, CD4(+) T cell destruction) occurring in tissues that are not easily accessible for analysis. In addition, although the disease can progress over years, many critical events happen within the first few weeks of infection, when most patients are unaware that they are infected. The nonhuman primate model of AIDS has been used extensively to fill these gaps in our understanding of AIDS pathogenesis.
Authors:
Andrew A Lackner; Ronald S Veazey
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Annual review of medicine     Volume:  58     ISSN:  0066-4219     ISO Abbreviation:  Annu. Rev. Med.     Publication Date:  2007  
Date Detail:
Created Date:  2007-02-15     Completed Date:  2007-04-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985151R     Medline TA:  Annu Rev Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  461-76     Citation Subset:  IM    
Affiliation:
Tulane National Primate Research Center, Covington, Louisiana 70433, USA. alackner@tulane.edu
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MeSH Terms
Descriptor/Qualifier:
Acquired Immunodeficiency Syndrome / etiology*
Animals
Disease Models, Animal*
HIV / physiology*
Humans
Macaca
Simian Acquired Immunodeficiency Syndrome*
Simian immunodeficiency virus / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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