Document Detail


Current challenges and unresolved problems in hypertensive disease.
MedLine Citation:
PMID:  19427489     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Over the past four or five decades, hypertension and cardiovascular medicine has experienced dramatic and innovative changes that have significantly reduced morbidity and mortality. A vast array of new antihypertensive compounds have been developed, which are able to inhibit many pathophysiologic mechanisms of the disease and prevent many of the outcomes in patients with hypertension. Much of this series of therapeutic breakthroughs have been the result of active participation of clinical scientists with tremendous and remarkable knowledge of and experience with the fundamental mechanisms of disease. In more recent years, much new information has appeared concerning the basis genetic and biologic mechanisms involved in cardiovascular and renal diseases. What remains of utmost importance is for members of the academic community with a wide spectrum of experience and points of view to continue to work with the fundamental problems and mechanisms of the diseases.
Authors:
Edward D Frohlich
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Medical clinics of North America     Volume:  93     ISSN:  1557-9859     ISO Abbreviation:  Med. Clin. North Am.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-11     Completed Date:  2009-06-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985236R     Medline TA:  Med Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  527-40, Table of Contents     Citation Subset:  AIM; IM    
Affiliation:
Ochsner Clinic Foundation, New Orleans, LA 70121, USA. efrohlich@ochsner.org
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MeSH Terms
Descriptor/Qualifier:
Antihypertensive Agents / therapeutic use
Humans
Hypertension / drug therapy,  etiology,  physiopathology*
Life Style
Obesity / complications
Risk Factors
Smoking / adverse effects
Sodium, Dietary / adverse effects
Chemical
Reg. No./Substance:
0/Antihypertensive Agents; 0/Sodium, Dietary

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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