Document Detail

Current treatment of venous thromboembolism.
MedLine Citation:
PMID:  20139364     Owner:  NLM     Status:  MEDLINE    
Venous thromboembolism, comprising deep vein thrombosis and pulmonary embolism, is a common disorder with at least 250 000 new events occurring each year in the United States alone. Treatment of venous thromboembolism includes anticoagulation, which is achieved initially with the use of a parenterally administered agent followed by a more prolonged course of treatment with an oral vitamin K antagonist. The duration of treatment depends on the clinical assessment of the benefit-to-risk ratio of prolonged anticoagulation versus the risk of recurrent events. In this review, we discuss some of the issues that we believe are among the most critical unanswered questions in the management of venous thromboembolism in the present era.
Nigel S Key; Raj S Kasthuri
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2010-02-05
Journal Detail:
Title:  Arteriosclerosis, thrombosis, and vascular biology     Volume:  30     ISSN:  1524-4636     ISO Abbreviation:  Arterioscler. Thromb. Vasc. Biol.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-19     Completed Date:  2010-04-01     Revised Date:  2013-05-31    
Medline Journal Info:
Nlm Unique ID:  9505803     Medline TA:  Arterioscler Thromb Vasc Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  372-5     Citation Subset:  IM    
Harold R. Roberts Distinguished Professor, Division of Hematology/Oncology, Department of Medicine, 932 Mary Ellen Jones Bldg, CB #7035, Chapel Hill, NC 27599, USA.
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MeSH Terms
Anticoagulants / therapeutic use*
Postthrombotic Syndrome / prevention & control
Recurrence / prevention & control
Venous Thrombosis / drug therapy*
Vitamin K / antagonists & inhibitors
Grant Support
Reg. No./Substance:
0/Anticoagulants; 12001-79-5/Vitamin K

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