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Current Status of Developments and Applications of Micro-CT.
MedLine Citation:
PMID:  21756145     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Use of microscopic computed-tomography (micro-CT) scanning continues to grow in biomedical research. Laboratory-based micro-CT scanners, laboratory-based nano-CT scanners, and integrated micro-CT/SPECT and micro-CT/PET scanners are now manufactured for "turn-key" operation by a number of commercial vendors. In recent years a number of technical developments in X-ray sources and X-ray imaging arrays have broadened the utility of micro-CT. Of particular interest are photon-counting and energy-resolving detector arrays. These are being explored to maximize micro-CT image grayscale dynamic range and to further increase image contrast by utilizing the unique spectral attenuation characteristics of individual chemical elements. X-ray phase-shift images may increase contrast resolution and reduce radiation exposure. Although radiation exposure is becoming a concern with the drive for increased spatial and temporal resolution, especially for longitudinal studies, gated scans and limited scan-data-set reconstruction algorithms show great potential for keeping radiation exposure to a minimum.
Authors:
Erik L Ritman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annual review of biomedical engineering     Volume:  13     ISSN:  1545-4274     ISO Abbreviation:  Annu Rev Biomed Eng     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883581     Medline TA:  Annu Rev Biomed Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  531-52     Citation Subset:  IM    
Affiliation:
Department of Physiology and Biomedical Engineering, Mayo Clinic, College of Medicine; Rochester, Minnesota 55905; email: elran@mayo.edu.
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