| The current spectrum of gastric polyps: a 1-year national study of over 120,000 patients. | |
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MedLine Citation:
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PMID: 19491866 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To use a large pathology database (Caris Diagnostics) to analyze the frequency and associations of gastric polyps in a nationwide US population. METHODS: A total of 121,564 esophagogastroduodenoscopy (EGD) procedures from private practices in 36 states in the Caris Diagnostics database from 1 April 2007 to 31 March 2008 were searched for the endoscopic designations of polyp, nodule, and mass, and for the pathological diagnoses that commonly present as gastric polyps. Pertinent demographic data, clinical indications for EGD, and information regarding Helicobacter pylori infection, reactive gastropathy, chronic inactive gastritis, and intestinal metaplasia were also obtained. RESULTS: A total of 78,909 of the 121,564 patients who underwent EGD had gastric biopsies. The prevalence of gastric polyps in the EGD population was 6.35%; 77% were fundic gland polyps, 17% hyperplastic polyps/polypoid foveolar hyperplasia, 0.69% adenomas, and 0.1% inflammatory fibroid polyps. Malignant neoplasms were slightly >2%. None of the benign gastric polyps had a significant positive association with concurrent H. pylori infection; intestinal metaplasia was detected in the background of 52.2% of carcinoids, 29.6% of adenomas, 20.1% of xanthomas, and 13% of adenocarcinomas and hyperplastic polyps. Adenomas were rarely associated with synchronous adenocarcinomas. CONCLUSIONS: The relative prevalence of fundic gland polyps in this population was much higher than that reported earlier, most likely because of the widespread use of proton pump inhibitors. H. pylori- and atrophy-associated polyps, including adenomas, were less common than in earlier series. |
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Authors:
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Susanne W Carmack; Robert M Genta; Christopher M Schuler; M Hossein Saboorian |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2009-04-28 |
Journal Detail:
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Title: The American journal of gastroenterology Volume: 104 ISSN: 1572-0241 ISO Abbreviation: Am. J. Gastroenterol. Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-06-03 Completed Date: 2009-06-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0421030 Medline TA: Am J Gastroenterol Country: United States |
Other Details:
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Languages: eng Pagination: 1524-32 Citation Subset: IM |
Affiliation:
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Department of Pathology, Veterans Affairs Medical Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Distribution Aged Aged, 80 and over Biopsy Child Child, Preschool Diagnosis, Differential Endoscopy, Gastrointestinal / methods Female Gastric Mucosa / pathology* Humans Infant Infant, Newborn Male Middle Aged Polyps / epidemiology*, pathology Population Surveillance / methods* Prevalence Retrospective Studies Sex Distribution Stomach Neoplasms / epidemiology*, pathology United States / epidemiology Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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