Document Detail

Current perspectives on diagnosis of heart failure in long-term dialysis patients.
MedLine Citation:
PMID:  21056523     Owner:  NLM     Status:  MEDLINE    
Cardiovascular disease is highly prevalent in patients with chronic kidney failure treated using dialysis. The risk of cardiovascular events is estimated to be at least 2- to 10-fold higher in dialysis patients than in age-, race-, and sex-matched persons with normal kidney function. A significant proportion of cardiovascular events in long-term dialysis patients is caused by heart failure, and the presence of heart failure is predictive of a poor prognosis. Despite the significant morbidity and mortality associated with heart failure, very few therapeutic options are proved to prevent and treat the progression of this complication in dialysis patients. There are several potential reasons for this, chiefly reflecting both challenges with diagnosis due to the coexistence of volume overload and a paucity of adequately powered prospective randomized controlled trials that examine the efficacy of different therapeutic options in dialysis patients with cardiac disease or heart failure. Thus, unlike in the general population, very few advances have been made in managing this severe complication in dialysis patients. In this article, an overview of the prevalence, severity, and risk factors for heart failure in maintenance dialysis patients is provided and the diagnosis of heart failure in these patients is revisited.
Angela Yee-Moon Wang; John E Sanderson
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-11-05
Journal Detail:
Title:  American journal of kidney diseases : the official journal of the National Kidney Foundation     Volume:  57     ISSN:  1523-6838     ISO Abbreviation:  Am. J. Kidney Dis.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-21     Completed Date:  2011-03-01     Revised Date:  2011-03-30    
Medline Journal Info:
Nlm Unique ID:  8110075     Medline TA:  Am J Kidney Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  308-19     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.
Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong.
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MeSH Terms
Heart Failure / diagnosis*,  epidemiology
Kidney Failure, Chronic / complications,  therapy*
Renal Dialysis*
Risk Factors
Severity of Illness Index
Time Factors
Erratum In:
Am J Kidney Dis. 2011 Mar;57(3):527

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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