Document Detail

Current outcomes of simultaneous carotid endarterectomy and coronary artery bypass graft surgery in North America.
MedLine Citation:
PMID:  20645099     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Management of patients with concomitant carotid and coronary artery disease has been controversial. Divergent strategies have been employed, including simultaneous carotid endarterectomy and coronary bypass (SCC) versus various staged procedures. Although no strict comparison group is available, this study defines current outcomes of SCC, compared qualitatively to two reference categories.
METHODS: Utilizing the STS database from 2003 to 2007, patients who had SCC were compared with patients with cerebrovascular disease who had coronary bypass (CABG) with prior carotid endarterectomy (CEA), and those with carotid Doppler stenosis >75% and no carotid intervention. Logistic regression analysis adjusted for differences in baseline characteristics and operative mortality (OM), and a composite of neurological complications (NC) was assessed.
RESULTS: Of 745,769 patients who underwent isolated CABG with/without CEA, 108,212 (14%) had cerebrovascular disease. Of this group, 5,732 (5%) underwent SCC. The SCC group had more males and lower preoperative risk factors. After statistical adjustment for all baseline differences, SCC had clinically and statistically higher OM and NC compared with any of the reference groups, with 20-40% higher event risk.
CONCLUSIONS: Although no quantitative control group exists for comparison, SCC as recently performed in North America has a high risk compared with any of the reference groups. Suboptimal results associated with the SCC strategy suggest a need for quality improvement and research on the optimal management of patients with simultaneous carotid and coronary disease.
Sunil M Prasad; Shuang Li; J Scott Rankin; Sean M O'Brien; James S Gammie; John D Puskas; David M Shahian; Edgar G Chedrawy; Malek G Massad
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of surgery     Volume:  34     ISSN:  1432-2323     ISO Abbreviation:  World J Surg     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-10     Completed Date:  2011-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7704052     Medline TA:  World J Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2292-8     Citation Subset:  IM    
Division of Cardiothoracic Surgery, University of Illinois at Chicago, 840 South Wood, CSB 417, Chicago, IL 60612, USA.
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MeSH Terms
Carotid Artery Diseases / complications,  surgery*
Coronary Artery Bypass*
Coronary Artery Disease / complications,  surgery*
Endarterectomy, Carotid*
Middle Aged
North America
Treatment Outcome

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