Document Detail

Curcumin as an amyloid-indicator dye in E. coli.
MedLine Citation:
PMID:  23287899     Owner:  NLM     Status:  MEDLINE    
We have demonstrated that curcumin is an amyloid-specific dye in E. coli. Curcumin binds to curliated whole cells and to isolated curli amyloid fibers. Similar to Congo red, curcumin exhibits a red-shift in absorbance and a significant increase in fluorescence upon binding to isolated curli.
Oscar A McCrate; Xiaoxue Zhou; Lynette Cegelski
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2013-01-04
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  49     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-04-22     Completed Date:  2013-10-23     Revised Date:  2014-10-26    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  England    
Other Details:
Languages:  eng     Pagination:  4193-5     Citation Subset:  IM    
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MeSH Terms
Amyloid / chemistry*,  metabolism
Benzenesulfonates / chemistry
Coloring Agents / chemistry*
Congo Red / chemistry
Curcumin / chemistry*
Escherichia coli / physiology*
Grant Support
DP2 OD007488/OD/NIH HHS; DP2 OD007488/OD/NIH HHS
Reg. No./Substance:
0/Amyloid; 0/Benzenesulfonates; 0/Coloring Agents; 3U05FHG59S/Congo Red; 4404-43-7/C.I. Fluorescent Brightening Agent 28; IT942ZTH98/Curcumin

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