Document Detail

Cupping of the optic disc in ischemic optic neuropathy.
MedLine Citation:
PMID:  929794     Owner:  NLM     Status:  MEDLINE    
Stereophotographs of the optic disc were reviewed in 78 patients with ischemic optic neuropathy (ION). Only 10% (6) of 61 nonarteritic (idiopathic) ION eyes developed optic disc cupping similar to that seen in glaucomatous eyes. Five of ten eyes with ION due to giant cell arteritis had cupping simulating glaucoma; however, two had elevated intraocular pressure, and the other three had large physiologic cups in the opposite eye. Optic disc pallor was proportionately more severe in ION eyes than in glaucomatous eyes of similar cup size. While there are similarities in the type of visual field loss in ION and glaucoma, the two disorders differ in the usual appearance of the disc after field loss has occurred and in the portion of the field most frequently affected. These observations suggest that if both disorders have an ischemic mechanism, there is a difference in the nature or distribution of the ischemia. There should be little difficulty under most circumstances in making the clinical differentiation between a disc that has suffered ION and a disc that has suffered pressure-induced damage, although occasional instances of ION may be classified as low-tension glaucoma on the basis of field loss and cupping without elevated intraocular pressure.
H Quigley; D R Anderson
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Transactions. Section on Ophthalmology. American Academy of Ophthalmology and Otolaryngology     Volume:  83     ISSN:  0161-6978     ISO Abbreviation:  Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol     Publication Date:    1977 Sep-Oct
Date Detail:
Created Date:  1978-01-27     Completed Date:  1978-01-27     Revised Date:  2008-02-26    
Medline Journal Info:
Nlm Unique ID:  101227536     Medline TA:  Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  755-62     Citation Subset:  IM    
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MeSH Terms
Acute Disease
Diagnosis, Differential
Fundus Oculi
Glaucoma / diagnosis*,  etiology
Ischemia / complications,  diagnosis*
Optic Disk* / blood supply
Optic Neuritis / diagnosis*,  etiology
Vision Disorders
Visual Acuity
Visual Fields

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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