| Cumulative probability of live birth after three in vitro fertilization/intracytoplasmic sperm injection cycles. | |
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MedLine Citation:
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PMID: 11872203 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To assess the probability of live birth after three available in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles. DESIGN: Retrospective, observational study. SETTING: University hospital. PATIENT(S): Nine hundred seventy-four couples who started their first conventional IVF or ICSI cycle between January 1996 and December 1997. A total of 1985 stimulated cycles were initiated. INTERVENTION(S): Analysis of the cumulative live birth rate using the life-table approach with and without taking dropouts into account. MAIN OUTCOME MEASURE(S): Cumulative live birth rate. RESULT(S): The overall cumulative live birth rate after three completed stimulated cycles (including freezing/thawing cycles) was 65.5% with an "optimistic" approach. For the "realistic" and "pessimistic" approaches the corresponding figures were 63.1% and 55.5%, respectively. Unexpectedly, 65% of couples not achieving a live birth interrupted the full treatment program of three cycles. CONCLUSION(S): The cumulative live birth rate gives the couple a more accurate prognosis of achieving a live birth after IVF/ICSI than the statistics usually provided. With the "realistic" estimation, 63% of the couples achieved childbirth after three available conventional IVF or ICSI cycles. Further studies are required to investigate the high drop-out rate. |
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Authors:
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Katarina Olivius; Barbro Friden; Kersti Lundin; Christina Bergh |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Fertility and sterility Volume: 77 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 2002 Mar |
Date Detail:
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Created Date: 2002-03-01 Completed Date: 2002-04-11 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 505-10 Citation Subset: IM |
Affiliation:
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Center for Reproductive Medicine, Sahlgrenska University Hospital, Göteborg University, Göteborg, Sweden. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Birth Rate* Cohort Studies Female Humans Infertility / therapy* Life Tables Male Ovulation Induction* Patient Dropouts Pregnancy Pregnancy Outcome Retrospective Studies Sperm Injections, Intracytoplasmic* Sweden |
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