| Cumulative first live birth after elective cryopreservation of all embryos due to ovarian hyperresponsiveness. | |
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MedLine Citation:
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PMID: 14967365 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To estimate cumulative chance for first live birth after elective pronuclear stage cryopreservation of all embryos due to ovarian hyperresponsiveness. DESIGN: Retrospective analysis with longitudinal follow-up. SETTING: Academic hospital. PATIENT(S): Thirty subjects with elective cryopreservation of all embryos due to ovarian hyperresponsiveness. INTERVENTION(S): Elective cryopreservation of all embryos at the pronuclear stage (n = 30) and subsequent cryopreserved-thawed ET (n = 51). MAIN OUTCOME MEASURE(S): Cumulative chance for first live birth. RESULT(S): Cumulative chance for first live birth was 77% when analyzed by intention to treat and 82% by treatment with ET. Nearly 40% of live births were multiple. CONCLUSION(S): Cumulative first live birth increased with repetitive ET after elective pronuclear stage cryopreservation of all embryos due to ovarian hyperresponsiveness. Multiple births, however, were frequent. In the context of initial ET attempts in young women, transfer of no more than two cryopreserved-thawed embryos is advised. |
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Authors:
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Ian S Tummon; Stephen A Contag; Alan R Thornhill; Donna R Session; Daniel A Dumesic; Mark A Damario |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Fertility and sterility Volume: 81 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 2004 Feb |
Date Detail:
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Created Date: 2004-02-17 Completed Date: 2004-03-24 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 309-14 Citation Subset: IM |
Affiliation:
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Mayo Clinic, Rochester, Minnesota 55905, USA. tummon.ian@mayo.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chorionic Gonadotropin / blood Cryopreservation / methods* Embryo Transfer Embryo, Mammalian* Estradiol / blood Female Fertilization in Vitro / methods* Follow-Up Studies Humans Infant, Newborn Longitudinal Studies Oocytes / cytology Ovarian Hyperstimulation Syndrome / physiopathology* Pregnancy Pregnancy Outcome* Retrospective Studies Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Chorionic Gonadotropin; 50-28-2/Estradiol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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