Document Detail


Cumulative effects of conjugated linoleic acid and exercise on endurance development, body composition, serum leptin and insulin levels.
MedLine Citation:
PMID:  17119522     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: The aim of this study was to evaluate the accruing effects of conjugated linoleic acid (CLA) supplementation and aerobic exercise (Ex) on body composition and serum lipid profile in humans. METHODS: Forty-four healthy female young subjects were divided ExCLA, CLA, Ex and control (C) groups. The groups of CLA and ExCLA were supplemented with 3.6 g/d CLA whilst ExCLA and Ex groups were exercised for 30 min(-1.)3 days(-1.)week(-1) for 6 weeks. RESULTS: After the study period, fat ratio, fat mass, waist and hip girths were reduced in all experimental groups and fat-free mass induced in ExCLA and CLA groups and body weight was reduced in the CLA group when compared to baseline levels. These alterations were significantly different than those of controls with the highest variations were observed in the ExCLA. There was no change in serum leptin, apo-AI, apo-B, total cholesterol, HDL, LDL, free fatty acid, and triglyceride levels. Serum glucose concentrations of ExCLA and CLA groups and insulin level of ExCLA group decreased significantly as compared to baseline levels with only serum glucose reduction of both groups were significantly different than those of controls (P<0.05). Endurance performance significantly increased in ExCLA and Ex groups (P<0.01) but did not vary in the CLA and controls. CONCLUSIONS: It was shown that both CLA and exercise were effective in improvement of body composition and these effects were cumulated when they have been used together. CLA supplementation alone or with exercise seems effective on serum glucose and insulin concentrations but ineffective on endurance performance.
Authors:
S Colakoglu; M Colakoglu; F Taneli; F Cetinoz; M Turkmen
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of sports medicine and physical fitness     Volume:  46     ISSN:  0022-4707     ISO Abbreviation:  J Sports Med Phys Fitness     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-22     Completed Date:  2007-03-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376337     Medline TA:  J Sports Med Phys Fitness     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  570-7     Citation Subset:  IM    
Affiliation:
School of Physical Education and Sports, Celal Bayar University, Manisa, Turkey. muzaffer@ege.edu,tr
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue / drug effects
Adult
Blood Glucose / drug effects
Body Composition / drug effects*
Exercise / physiology*
Female
Humans
Insulin / blood
Leptin / blood
Linoleic Acids, Conjugated / pharmacology*
Lipids / blood
Physical Endurance / drug effects*
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Leptin; 0/Linoleic Acids, Conjugated; 0/Lipids; 11061-68-0/Insulin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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