Document Detail

Cumulative dietary exposure to a selected group of pesticides of the triazole group in different European countries according to the EFSA guidance on Probabilistic modelling.
MedLine Citation:
PMID:  25125392     Owner:  NLM     Status:  Publisher    
The practicality was examined of performing a cumulative dietary exposure assessment according to the requirements of the EFSA guidance on probabilistic modelling. For this the acute and chronic cumulative exposure to triazole pesticides was estimated using national food consumption and monitoring data of eight European countries. Both the acute and chronic cumulative dietary exposures were calculated according to two model runs (optimistic and pessimistic) as recommended in the EFSA guidance. The exposures obtained with these model runs differed substantially for all countries, with the highest exposures obtained with the pessimistic model run. In this model run, animal commodities including cattle milk and different meat types, entered in the exposure calculations at the level of the maximum residue limit (MRL), contributed most to the exposure. We conclude that application of the optimistic model run on a routine basis for cumulative assessments is feasible. The pessimistic model run is laborious and the exposure results could be too far from reality. More experience with this approach is needed to stimulate the discussion of the feasibility of all the requirements, especially the inclusion of MRLs of animal commodities which seem to result in unrealistic conclusions regarding their contribution to the dietary exposure.
Polly E Boon; Gerda van Donkersgoed; Despo Christodoulou; Amélie Crépet; Laura D'Addezio; Virginie Desvignes; Bengt-Göran Ericsson; Francesco Galimberti; Eleni Ioannou- Kakouri; Bodil Hamborg Jensen; Irena Rehurkova; Josselin Rety; Jiri Ruprich; Salomon Sand; Claire Stephenson; Anita Strömberg; Aida Turrini; Hilko van der Voet; Popi Ziegler; Paul Hamey; Jacob D van Klaveren
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-8-11
Journal Detail:
Title:  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association     Volume:  -     ISSN:  1873-6351     ISO Abbreviation:  Food Chem. Toxicol.     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-8-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8207483     Medline TA:  Food Chem Toxicol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014. Published by Elsevier Ltd.
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