Document Detail


Cultures of Holder-Pasteurized Donor Human Milk After Use in a Neonatal Intensive Care Unit.
MedLine Citation:
PMID:  22424470     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objective: Current guidelines state that human milk, once thawed, should be kept in a refrigerator for only 24 hours. We cultured Holder-pasteurized donor human milk (DHM) after thawing and refrigeration under clinical conditions. Study Design: Bottles of pasteurized DHM were thawed and used in a Regional Level 3 neonatal intensive care unit (NICU) in standard clinical fashion and kept refrigerated when not in use. Once no longer needed clinically, aliquots were cultured for bacteria. Results: In total, 30 bottles were returned for culture; six were excluded from analysis because human milk fortifier had been added, and two had been left out of the refrigerator. The remaining 22 bottles were culture-negative after having been thawed for 7-122 hours. Conclusions: DHM without additives was culture-negative for 24 hours or longer after thawing and routine NICU handling. These data indicate that unfortified Holder-pasteurized DHM handled appropriately and refrigerated remains sterile for 24 hours after thawing and perhaps longer. Further study is needed to confirm this.
Authors:
Ronald S Cohen; Chien-Fang Riva Huang; Sean C Xiong; Pauline Sakamoto
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-16
Journal Detail:
Title:  Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine     Volume:  -     ISSN:  1556-8342     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101260777     Medline TA:  Breastfeed Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
1 Neonatal and Developmental Medicine, Stanford University School of Medicine , Palo Alto, California.
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