Document Detail


Cultured cell lines for research on pulmonary physiology available through the American type culture collection.
MedLine Citation:
PMID:  7065527     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Procedures are described by which cell lines of potential use for studies on pulmonary physiology were developed or otherwise obtained, characterized, and banked for distribution to the scientific community. Seventy-seven cell lines were submitted under this program. Forty-eight of these exhibited adequate doubling potential and were of sufficient interest and purity to permit accessioning and banking for distribution. An additional 12 lung cell lines had been added earlier during development of the Cell Repository. In all, 4 presumptive type II alveolar lines, 2 nonspecified epithelial-like lines, 2 endothelial lies, 1 mesothelial line, and 51 fibroblastlike lines are available. Eighteen species including humans, monkeys, and common laboratory animals are represented. An additional 19 lines were retained as token holdings because they either exhibited insufficient doubling potential or represented duplicate samples of differing passage levels. Ten lines were rejected because of poor viability, presence of contaminant microorganisms, or inappropriate species identification by the donor. The lines will be retained at the ATCC for distribution on request to the scientific community at large. As newly developed strains are identified and made available these may also be added to the existing collection. Appropriate cooperation from the scientific community and support from governmental funding agencies are required and acknowledge.
Authors:
R J Hay; C D Williams; M L Macy; K S Lavappa
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American review of respiratory disease     Volume:  125     ISSN:  0003-0805     ISO Abbreviation:  Am. Rev. Respir. Dis.     Publication Date:  1982 Feb 
Date Detail:
Created Date:  1982-05-21     Completed Date:  1982-05-21     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370523     Medline TA:  Am Rev Respir Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  222-32     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Animals
Bronchi / cytology
Cats
Cattle
Cell Line
Cells, Cultured*
Cercopithecus aethiops
Child
Child, Preschool
Chiroptera
Cricetinae
Endothelium / cytology
Female
Fetus / cytology
Fibroblasts / cytology
Foxes
Guinea Pigs
Humans
Lizards
Lung / physiology*
Macaca mulatta
Mice
Middle Aged
Pulmonary Alveoli / cytology
Rabbits
Rats / embryology
Rats, Inbred F344
Saimiri
Grant Support
ID/Acronym/Agency:
N01-HR-6-2930/HR/NHLBI NIH HHS; N01-RR-9-2104/RR/NCRR NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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