Document Detail


Cultivation-independent analysis of changes in bacterial vaginosis flora following metronidazole treatment.
MedLine Citation:
PMID:  17202272     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PCR was used to survey bacterial vaginosis flora before and after metronidazole treatment. The species composition for pretreatment patients was variable. Lactobacillus iners was prominent in all patients posttreatment. Atopobium vaginae concentrations were highest for patients who failed or responded incompletely to treatment and lowest for patients who were cured.
Authors:
Michael J Ferris; Johana Norori; Marcela Zozaya-Hinchliffe; David H Martin
Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, N.I.H., Extramural     Date:  2007-01-03
Journal Detail:
Title:  Journal of clinical microbiology     Volume:  45     ISSN:  0095-1137     ISO Abbreviation:  J. Clin. Microbiol.     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-03-05     Completed Date:  2007-05-10     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7505564     Medline TA:  J Clin Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1016-8     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Louisiana State University Health Sciences Center, New, Orleans, Louisiana 70112, USA. mferris@chnola-research.org
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MeSH Terms
Descriptor/Qualifier:
Actinobacteria / genetics,  growth & development,  isolation & purification*
Anti-Infective Agents / therapeutic use*
DNA, Bacterial / analysis
Female
Humans
Lactobacillus / genetics,  growth & development,  isolation & purification*
Metronidazole / therapeutic use*
Polymerase Chain Reaction / methods*
Treatment Outcome
Vaginosis, Bacterial / drug therapy*,  microbiology*
Grant Support
ID/Acronym/Agency:
U19AI061972/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/Anti-Infective Agents; 0/DNA, Bacterial; 443-48-1/Metronidazole
Comments/Corrections

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