| Culprit only or multivessel percutaneous coronary interventions in patients with ST-segment elevation myocardial infarction and multivessel disease. | |
| | |
MedLine Citation:
|
PMID: 22917729 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Aims: In patients with ST-segment elevation myocardial infarction (STEMI), timely reperfusion with primary percutaneous coronary intervention (PPCI) is the preferred treatment. However, it remains unclear whether the optimal strategy is complete revascularisation or culprit vessel PPCI only. Methods and results: From January 2002 to June 2009 all patients treated with PPCI were identified from the Western Denmark Heart Registry. We examined mortality according to timing of multivessel PCI: acute procedure, staged procedure during the index hospitalisation, or staged procedure performed within 60 days. The hazard ratio (HR) for death was estimated using a time-dependent Cox regression model, with time of PCI for the non-culprit lesion as the time-dependent variable. The study cohort consisted of 5,944 patients, of whom 4,770 (80%) had single-vessel disease and 1,174 (20%) had multivessel PCI within 60 days. Among 354 (30.2%) patients with acute multivessel PCI, 194 (16.5%) patients with multivessel PCI during the index hospitalisation, and 626 (53.3%) patients with multivessel PCI within 60 days after the index hospitalisation, the adjusted HRs for one-year mortality were 1.53 (95% confidence interval (CI): 1.07-2.18), 0.60 (95% CI: 0.28-1.26), and 0.28 (95% CI: 0.14-0.54), respectively, compared to patients with single vessel disease. Conclusions: Acute multivessel PCI in patients with STEMI was associated with increased mortality. |
| | |
Authors:
|
Lisette Okkels Jensen; Per Thayssen; Dóra Körmendiné Farkas; Mikkel Hougaard; Christian Juhl Terkelsen; Hans-Henrik Tilsted; Michael Maeng; Anders Junker; Jens Flensted Lassen; Erzsébet Horváth-Puhó; Henrik Toft Sørensen; Leif Thuesen |
Related Documents
:
|
22595319 - Prevalence of kawasaki disease in young adults with suspected myocardial ischemia. 15361769 - Evidence against a major role for angiotensin converting enzyme-related carboxypeptidas... 22420239 - Biomarkers of inflammation and cardiac remodeling: the quest of relevant companions for... 22029669 - Safety and feasibility of percutaneous retrograde coronary sinus delivery of autologous... 21051889 - From evidence to rationale: cardiovascular protection by angiotensin ii receptor blocke... 22870739 - Cardiac resynchronization therapy in clinical responders: right ventricular echocardiog... 8960449 - Angina in the elderly. 22079089 - Thrombolytic treatment of simultaneous pulmonary embolism and impending paradoxical emb... 8570929 - Emergent care of lightning and electrical injuries. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology Volume: 8 ISSN: 1969-6213 ISO Abbreviation: EuroIntervention Publication Date: 2012 Aug |
Date Detail:
|
Created Date: 2012-08-24 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101251040 Medline TA: EuroIntervention Country: France |
Other Details:
|
Languages: eng Pagination: 456-64 Citation Subset: IM |
Affiliation:
|
Department of Cardiology, Odense University Hospital, Odense, Denmark. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Paclitaxcel-coated balloon plus bare metal stent vs. sirolimus-eluting stent in de novo lesions: an ...
Next Document: Contemporary use and outcome of percutaneous coronary interventions in patients with acute coronary ...