Document Detail


Crystallization of community-acquired respiratory distress syndrome toxin from Mycoplasma pneumoniae.
MedLine Citation:
PMID:  20208164     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Community-acquired respiratory distress syndrome toxin (CARDS TX) is a 591-amino-acid protein with ADP-ribosyltransferase and vacuolating activities that damages the cells lining the respiratory tracts of patients infected with the bacterial pathogen Mycoplasma pneumoniae. Crystals of CARDS TX were grown in space group C2, with unit-cell parameters a = 191.4, b = 107.4, c = 222.1 A, beta = 90.6 degrees. A complete 2.2 A data set was obtained from a single CARDS TX crystal.
Authors:
Olga N Pakhomova; Alexander B Taylor; Argentina Becker; Stephen P Holloway; T R Kannan; Joel B Baseman; P John Hart
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2010-02-24
Journal Detail:
Title:  Acta crystallographica. Section F, Structural biology and crystallization communications     Volume:  66     ISSN:  1744-3091     ISO Abbreviation:  Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-08     Completed Date:  2010-04-05     Revised Date:  2012-03-01    
Medline Journal Info:
Nlm Unique ID:  101226117     Medline TA:  Acta Crystallogr Sect F Struct Biol Cryst Commun     Country:  England    
Other Details:
Languages:  eng     Pagination:  294-6     Citation Subset:  IM    
Affiliation:
Department of Biochemistry, University of Texas Health Science Center, San Antonio, TX 78229, USA.
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MeSH Terms
Descriptor/Qualifier:
ADP Ribose Transferases / chemistry*
Bacterial Proteins / chemistry*
Bacterial Toxins / chemistry*
Crystallography, X-Ray
Mycoplasma pneumoniae / enzymology*
Ultracentrifugation
Grant Support
ID/Acronym/Agency:
U19 AI070412/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/Bacterial Proteins; 0/Bacterial Toxins; 0/CARDS toxin, Mycoplasma pneumoniae; EC 2.4.2.-/ADP Ribose Transferases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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