| Cryptogenic organizing pneumonia: clinical profile in a series of 34 admitted patients in a hospital in India. | |
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MedLine Citation:
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PMID: 18702383 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: Cryptogenic Organizing Pneumonia (COP) is a relatively rare disorder which is gratifying to treat due to its prompt steroid responsiveness. There have been only 2 case reports on COP from India but no large series entity reported from this country. METHODS: The medical records of all patients with biopsy (histopathology) proven COP admitted in a tertiary care hospital in Mumbai (2000-2005) were retrospectively analyzed. We looked at clinical and radiographic profiles, initial diagnosis and treatment, lag period to starting definitive therapy and steroid responsiveness. RESULTS: When compared to other series of patients with COP, our series showed several similarities and some differences. Distinctive features were the striking female preponderance and the utility of transbronchial biopsies in establishing the diagnosis. Long delays in diagnosis with patients mislabeled as tuberculosis or pneumonia, lead to delays in starting steroids resulting in 21% of our patients continuing to deteriorate. CONCLUSIONS: This comprehensive review of COP, the first of its kind from India, reveals its varied clinical and radiographic spectrum. A high index of suspicion will lead to prompt steroid therapy which will result in better patient outcome. |
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Authors:
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T Sen; Z F Udwadia |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of the Association of Physicians of India Volume: 56 ISSN: 0004-5772 ISO Abbreviation: J Assoc Physicians India Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-08-15 Completed Date: 2008-09-12 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 7505585 Medline TA: J Assoc Physicians India Country: India |
Other Details:
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Languages: eng Pagination: 229-32 Citation Subset: IM |
Affiliation:
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P. D. Hinduja Hospital and National Research Centre, Mahim, Mumbai. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Cryptogenic Organizing Pneumonia* / diagnosis, therapy Female Humans Male Middle Aged |
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