Document Detail


Cryptococcus neoformans: gastronomic delight of a soil ameba.
MedLine Citation:
PMID:  394365     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
During 7 days of incubation in vitro the trophozoite stage of the free-living soil amoeba, Acanthamoeba polyphaga, phagocytized and killed 78-97% of the cells of three strains of Cryptococcus neoformans. With one strain, incubation time was increased to nine days and 99% of the yeast cells were killed. It was calculated that during 4-9 days of incubation a single trophozoite phagocytized and killed a daily average of 84 yeast cells. The lethal effect of A. polyphaga on C. neoformans may represent a biological control mechanism in nature. Some of the surviving cells of C. neoformans developed into colonies containing pseudohyphae; these pseudolhyphal forms may be a biological 'escape hatch'.
Authors:
L A Bunting; J B Neilson; G S Bulmer
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Sabouraudia     Volume:  17     ISSN:  0036-2174     ISO Abbreviation:  Sabouraudia     Publication Date:  1979 Sep 
Date Detail:
Created Date:  1980-04-17     Completed Date:  1980-04-17     Revised Date:  2007-04-30    
Medline Journal Info:
Nlm Unique ID:  0417341     Medline TA:  Sabouraudia     Country:  SCOTLAND    
Other Details:
Languages:  eng     Pagination:  225-32     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Amoeba / physiology*
Animals
Cryptococcus / physiology*
Cryptococcus neoformans / growth & development,  physiology*
Phagocytosis*
Soil Microbiology*

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