Document Detail


Cryptococcosis in tree shrews (Tupaia tana and Tupaia minor) and elephant shrews (Macroscelides proboscides).
MedLine Citation:
PMID:  9279407     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fungal infections due to Cryptococcus neoformans occurred in seven short-eared elephant shrews (Macroscelides proboscides), six large tree shrews (Tupaia tana), and five lesser tree shrews (Tupaia minor) at the National Zoological Park during a 30-mo period in 1991-1993. Clinical signs were absent or included weight loss, shivering, dyspnea, and/or neurologic disease. Definitive antemortem diagnostic techniques included tracheal lavage and serum cryptococcal antigen latex agglutination titers. Thirteen cases were diagnosed solely by postmortem examination. The source of infection for these animals was uncertain, but C. neoformans is commonly found in soil and other organic material. Two lesser tree shrews and one large tree shrew received antifungal therapy and converted to a negative serum cryptococcal antigen titer.
Authors:
L A Tell; D K Nichols; W P Fleming; M Bush
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians     Volume:  28     ISSN:  1042-7260     ISO Abbreviation:  J. Zoo Wildl. Med.     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1997-09-30     Completed Date:  1997-09-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8915208     Medline TA:  J Zoo Wildl Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  175-81     Citation Subset:  IM    
Affiliation:
Department of Animal Health, National Zoological Park, Washington, D.C. 20008, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Animals, Zoo*
Antifungal Agents / therapeutic use
Cryptococcosis / drug therapy,  pathology,  veterinary*
District of Columbia
Female
Fluconazole / therapeutic use
Male
Tupaia*
Tupaiidae*
Chemical
Reg. No./Substance:
0/Antifungal Agents; 86386-73-4/Fluconazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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