Document Detail

Cryptococcal pyelonephritis in a dog.
MedLine Citation:
PMID:  12555981     Owner:  NLM     Status:  MEDLINE    
A 5-year-old castrated male Golden Retriever was evaluated for polyuria, polydipsia, and progressive regurgitation thought to be a result of bacterial pyelonephritis and megaesophagus. Bacteriologic culture of urine failed to yield clinically relevant growth, and results of a urine sediment examination were normal. With time, intention tremors and progressive neurologic dysfunction were also observed. At necropsy, a diagnosis of cryptococcal disease was confirmed histologically and immunohistochemically. Findings in the dog of this report were indicative of nephrogenic diabetes insipidus with polyuria and polydipsia caused by cryptococcal pyelonephritis. Neurologic manifestations of systemic cryptococcus infection included megaesophagus, esophageal hypomotility, and regurgitation attributed to localization of cryptococcal organisms in the brain stem in the region of the dorsal motor nucleus of the vagus nerve. To the authors' knowledge, this is the first report of polyuria secondary to cryptococcal pyelonephritis.
Shelley J Newman; Cathy E Langston; Timothy J Scase
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Veterinary Medical Association     Volume:  222     ISSN:  0003-1488     ISO Abbreviation:  J. Am. Vet. Med. Assoc.     Publication Date:  2003 Jan 
Date Detail:
Created Date:  2003-01-30     Completed Date:  2003-04-22     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7503067     Medline TA:  J Am Vet Med Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  180-3, 174     Citation Subset:  IM    
Department of Pathology, Bobst Hospital, The Animal Medical Center, 510 E 62nd St, New York, NY 10021-8314, USA.
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MeSH Terms
Central Nervous System Fungal Infections / etiology,  microbiology,  veterinary
Cryptococcosis / complications,  veterinary*
Diagnosis, Differential
Dog Diseases / etiology,  microbiology*
Esophageal Achalasia / complications,  microbiology,  veterinary*
Fatal Outcome
Immunohistochemistry / veterinary
Kidney / pathology
Polyuria / etiology,  veterinary
Pyelonephritis / complications,  microbiology,  veterinary*
Urinalysis / veterinary

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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