Document Detail

Cryptococcal meningitis in systemic lupus erythematosus.
MedLine Citation:
PMID:  1411578     Owner:  NLM     Status:  MEDLINE    
Two cases of cryptococcal meningitis occurring in patients with systemic lupus erythematosus (SLE) are presented, and 24 additional cases from the literature are reviewed. The insidious onset of this infrequent complication is emphasized. The nonspecific neurological findings associated with this infection are often mistakenly diagnosed as a central nervous system manifestation of SLE. Earlier diagnosis and effective antifungal therapy have improved the prognosis of cryptococcal meningitis in SLE patients in recent years. Strategies for the treatment of patients with this complication are discussed.
B Zimmermann; M Spiegel; E V Lally
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Seminars in arthritis and rheumatism     Volume:  22     ISSN:  0049-0172     ISO Abbreviation:  Semin. Arthritis Rheum.     Publication Date:  1992 Aug 
Date Detail:
Created Date:  1992-10-30     Completed Date:  1992-10-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1306053     Medline TA:  Semin Arthritis Rheum     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  18-24     Citation Subset:  IM    
Department of Medicine, Roger Williams Medical Center, Providence, RI 02908.
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MeSH Terms
Amphotericin B / therapeutic use
Cryptococcus / isolation & purification
Flucytosine / therapeutic use
Lupus Erythematosus, Systemic / complications*
Meningitis, Cryptococcal / cerebrospinal fluid,  complications*,  drug therapy
Prednisone / therapeutic use
Reg. No./Substance:
1397-89-3/Amphotericin B; 2022-85-7/Flucytosine; 53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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