| Cryptococcal meningitis in HIV negative pregnant women: case report and review of literature. | |
| | |
MedLine Citation:
|
PMID: 19893983 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
INTRODUCTION: Cryptococcosis has become an important entity due to the epidemic of AIDS and therefore it is a significant opportunistic infection. However, there are case reports of cryptococcal meningitis in immune competent pregnant women. Since pregnancy is considered a period of relative immunosuppression, which likely prevents fetal rejection, this could explain the occurrence of opportunistic infections. OBJECTIVE: To report a case of cryptococcosis, and review all cases involving pregnancy and neurocryptococcal infection in immune competent pregnant patients. METHODS: Case report and systematic review of the literature using the MEDLINE and SciELO databases. DISCUSSION: A total of 27 patients were analyzed from 19 studies. The mean age at diagnosis was 26.4 years. There were six patients in their first trimester of pregnancy, 10 in the second, eight in the third and three post-partum. The most prevalent symptoms were headache (85.2%), altered vision (44.4%), altered mental status (44.4%), nausea (40.7%) and fever (33.3%). There were nine deaths (33.3%). Most of the patients received intravenous amphotericin B as treatment (77.8%). The majority (66.6%) of the patients accomplished a term delivery with healthy infants. CONCLUSION: Cryptococcal meningitis should be considered during pregnancy in cases of unexplained headache, altered vision, altered mental status, nausea and fever. Patients with a confirmed diagnosis should be admitted and treated with amphotericin B. |
| | |
Authors:
|
Maria Laura Botelho Costa; João Paulo Dias de Souza; Antônio Francisco de Oliveira Neto; João Luiz Pinto E Silva |
Related Documents
:
|
4092703 - Pasteurella ureae meningitis as complication of skull fractures. 15301673 - Adult bacterial meningitis: aetiology, penicillin susceptibility, risk factors, prognos... 11298643 - Leishmania-sand fly interactions controlling species-specific vector competence. |
Publication Detail:
|
Type: Case Reports; Journal Article; Review |
Journal Detail:
|
Title: Revista do Instituto de Medicina Tropical de São Paulo Volume: 51 ISSN: 1678-9946 ISO Abbreviation: Rev. Inst. Med. Trop. Sao Paulo Publication Date: 2009 Sep-Oct |
Date Detail:
|
Created Date: 2009-11-06 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7507484 Medline TA: Rev Inst Med Trop Sao Paulo Country: Brazil |
Other Details:
|
Languages: eng Pagination: 289-94 Citation Subset: IM |
Affiliation:
|
Department of Gynecology and Obstetrics, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil. mlaura@unicamp.br |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Serology using rROP2 antigen in the diagnostic of toxoplasmosis in pregnant women.
Next Document: Accidental infection by Trypanosoma cruzi follow-up by the polymerase chain reaction: case report.