Document Detail


Cryptococcal immune reconstitution syndrome during steroid withdrawal treated with hydroxychloroquine.
MedLine Citation:
PMID:  21094071     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We present a case report of cryptococcal immune reconstitution syndrome (IRS), in a non HIV infected patient, which we treated with hydroxychloroquine with successful results. We briefly review cryptococcal IRS, possible mechanisms of action of hydroxychloroquine as an immunomodulatory agent, and its potential role in management of IRS.
Authors:
Shivakumar Narayanan; Chandralekha Banerjee; Peter A Holt
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-11-19
Journal Detail:
Title:  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases     Volume:  15     ISSN:  1878-3511     ISO Abbreviation:  Int. J. Infect. Dis.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-10     Completed Date:  2011-04-18     Revised Date:  2012-01-11    
Medline Journal Info:
Nlm Unique ID:  9610933     Medline TA:  Int J Infect Dis     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  e70-3     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Department of Internal Medicine, Good Samaritan Hospital of Maryland, 5601 Loch Raven Boulevard, RMB, Ste 502, Baltimore, MD 21239, USA. shivakumar.narayanan@medstar.net
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MeSH Terms
Descriptor/Qualifier:
Aged
Anti-Inflammatory Agents / administration & dosage
Antifungal Agents / therapeutic use*
Cryptococcosis / diagnosis*,  drug therapy*
Cryptococcus neoformans / isolation & purification
Female
Granuloma / microbiology,  pathology
Humans
Hydroxychloroquine / therapeutic use*
Hypercalcemia
Immune Reconstitution Inflammatory Syndrome / diagnosis*,  drug therapy*
Immunologic Factors / therapeutic use*
Lung / microbiology,  physiopathology
Prednisone / administration & dosage
Skin / microbiology,  pathology
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Antifungal Agents; 0/Immunologic Factors; 118-42-3/Hydroxychloroquine; 53-03-2/Prednisone
Comments/Corrections
Comment In:
Int J Infect Dis. 2011 Dec;15(12):e884   [PMID:  21982695 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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