| Cryotop vitrification of human oocytes results in high survival rate and healthy deliveries. | |
| | |
MedLine Citation:
|
PMID: 17207335 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Vitrification, an ultra-rapid cooling technique, offers a new perspective in attempts to develop an optimal cryopreservation procedure for human oocytes and embryos. To further evaluate this method for human oocytes, 796 mature oocytes (metaphase II) were collected from 120 volunteers. Since Italian legislation allows the fertilization of a maximum of only three oocytes per woman, there were 463 supernumerary oocytes; instead of being discarded, they were vitrified. When, in subsequent cycles, these oocytes were utilized, 328 out of 330 (99.4%) oocytes survived the warming procedure. The fertilization rate, pregnancy rate and implantation rate per embryo were 92.9, 32.5 and 13.2% respectively. Thus, as already reported in the literature, the vitrification procedure seems to be highly effective, safe (since healthy babies have been born) and easy to apply. In situations where embryo cryopreservation is not permitted (as in Italy), there is now good indication for routine application of the method, once further standardization is achieved. |
| | |
Authors:
|
Monica Antinori; Emanuele Licata; Gianluca Dani; Fabrizio Cerusico; Caterina Versaci; Severino Antinori |
Related Documents
:
|
15493565 - Efficacy of recombinant human follicle-stimulating hormone in improving oocyte quality ... 1628945 - An irish out-patient based in-vitro fertilisation service. 9250485 - Simple and efficient vitrification procedure for cryopreservation of mouse embryos. 2976225 - Transvaginal ultrasound or laparoscopy for oocyte retrieval (experiences in the ljublja... 2453005 - Second-trimester maternal serum alpha-fetoprotein levels in pregnancies associated with... 8218005 - Stereomicroscopic demonstration of chorionic villi: differentiation between miscarriage... |
Publication Detail:
|
Type: Evaluation Studies; Journal Article |
Journal Detail:
|
Title: Reproductive biomedicine online Volume: 14 ISSN: 1472-6483 ISO Abbreviation: Reprod. Biomed. Online Publication Date: 2007 Jan |
Date Detail:
|
Created Date: 2007-01-08 Completed Date: 2007-02-28 Revised Date: 2009-07-20 |
Medline Journal Info:
|
Nlm Unique ID: 101122473 Medline TA: Reprod Biomed Online Country: England |
Other Details:
|
Languages: eng Pagination: 72-9 Citation Subset: IM |
Affiliation:
|
International Associated Research Institute for Human Reproduction Infertility Unit Day Hospital, Via Timavo No.2, Rome, Italy. monica_antinori@hotmail.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cell Culture Techniques Cryopreservation / instrumentation, methods*, standards Embryo Implantation Female Fertilization Humans Oocytes* Pregnancy Pregnancy Rate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Differential sucrose concentration during dehydration (0.2 mol/l) and rehydration (0.3 mol/l) increa...
Next Document: Air fluid versus fluid-only models of embryo catheter loading: a systematic review and meta-analysis...